• br Both cells cultured under normoxic

  2020-08-30

  

  Both LY 500307 cultured under normoxic condition on random fiber substrates (R-PLLA and R-PCL) produce less spread and more Fig. 4. Quantification of the cellular morphologies of cytoplasm roundness ((a) and (a’)), cytoplasm elongation factor ((b) and (b’)), nuclear elongation factor ((c) and

• br result of coronary vasospasm and possibly also

  2020-08-28

  

  result of coronary vasospasm, and possibly also induce acute myocardial infarction and arrhythmias. Cardiotoxicity from antimetabolites in-volves also ROS formation, mitochondrial dysfunction, lipid peroxida-tion and DNA damage [57]. Organic nitrates can be used to prevent vasospasm in 5-fluoroura

• br ROS is well known ER

  2020-08-28

  

  ROS is well-known ER stress inducer [35]. ER stress triggers the activation of UPR, which functions as an adaptive response and further leads to apoptosis [35]. UPR is distinguished by three ER transmem-brane receptor proteins, namely, IRE1α, PERK, and ATF6 [21]. In resting cells, all three recept

• br Results and discussion br Characterization of

  2020-08-28

  

  2. Results and discussion 2.1. Characterization of R646/siRNA nanoparticles Bioreducible PBAEs were synthesized via polymerization of monomer bis(2-hydroxyethyl) disulfide (BR6) with monomer 4-amino-1-butanol (S4), followed by polymer end-capping with 2-((3-amino-propyl)amino)ethanol (E6), t

• br A Cruz Berm dez et al br Fig The

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  A. Cruz-Bermúdez et al. Fig. 4. The role of Fibroblast OXPHOS function in metabolic re- programming of co-cultured cells. (A) OXPHOS function character-ization of fibroblast cell lines. (CF1; Control Fibroblast 1, CF1 +EtBr; Control Fibroblast 1 + Ethidium Bromide, AF; Affected Fibroblast). N

• br Radiomics there will be a continued search for

  2020-08-18

  

  Radiomics - there will be a continued search for quantitative image features having observable biological correlates Radiomics is a recent buzzword for the extraction and applica-tion of a large number of quantitative image features. Radiomics can potentially be used to improve diagnosis, chara

• br The aim of this study was the construction of

  2020-08-18

  

  The aim of this study was the construction of a breast-cancer tar-geted, biocompatible nanoparticle vehicle with minimum toxicity to non-specific tissues. Herein, bombesin was conjugated to the EGCG-encapsulated SLN system and bombesin-conjugated solid lipid nano-particles were then explored for t

• br K Balasubramanian Notes Theoretical calculations on the t

  2020-08-18

  

  [37] K. Balasubramanian, Notes Theoretical calculations on the transition energies of the D. Lachowicz et al. Contents lists available at ScienceDirect Clinical Nutrition Original article Body composition, dietary intake and physical activity of young survivors of childhood cancer

• br Time Lapse Microscopy br

  2020-08-18

  

  Time-Lapse Microscopy Thymidine-synchronized ovarian cells expressing mCherry-histone H2B were released for 5 hours, treated either with single agents or combinations. For time-lapse analysis, the treated cells were transferred to the microscope stage, and microscopy was performed with Axioimag

• br AUTHOR CONTRIBUTIONS br DECLARATION OF INTERESTS br

  2020-08-18

  

  AUTHOR CONTRIBUTIONS DECLARATION OF INTERESTS The authors declare no competing interests. REFERENCES Finkel, T. (2011). 846557-71-9 by reactive oxygen species. J. Cell Biol. Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. (1994). The effect of vitamin E and beta caro

• br GL T Mediated Functional Delivery

  2020-08-18

  

  GL21.T-Mediated Functional Delivery of miR-137 in NSCLC As a next step, we confirmed that GL21.T-137 increases intracellular miR-137 levels at a comparable extent of a commercial miR-137 mimic upon transfection (Figure S2), thus preserving miR moiety function as well. Thus, we analyzed whether

• br Because I found out that if

  2020-08-18

  

  “Because I found out that if I burned 1, 2, 3, 4, 5, 600 calories every hour, then I would not be able to catch up (with that). Meaning, I would experience a bigger weight loss by exercising. I simply could not afford it. So, I stopped” (ID 13, 69-year-old male with pancreatic cancer) Despite po

• br In addition as explained by

  2020-08-18

  

   In addition, as explained by previous research, patients' perceptions may be confounded by individual characteristics such as gender and marital status (Rose, 2018), the patients’ culture and ethnic origin (Astrow et al., 2018; Radwin et al., 2013), the type of cancer and treatment characterist

• br We hypothesized that TP

  2020-08-18

  

  We hypothesized that TP53 mutational status determined by routine targeted next-generation sequencing (NGS) diagnosis may correlate with response to ICI (either as monotherapy or double PD-1 and CTLA-4 blockade). We focused on aNSCLC patients treated in a University center, either in registered in

• br Results from our study

  2020-08-14

  

  Results from our study support previous reports that tooth loss was significantly associated with increased lung cancer risk. In the Health Professionals Follow-Up Study, among European American male po-pulations with high educational attainment, having fewer teeth was associated with an increased

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